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Although promotion of angiogenesis and cell proliferation could entail benefits in the short-term in terms of tissue healing, this could be a double-edged sword, as these same processes are how many cancers initiate and spread

Ultrasound-guided injections or the use of epinephrine before surgery can reduce vascular damage [16]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Liu X, Olszewski K, Zhang Y, Lim EW, Shi J, Zhang X, Zhang J, Lee H, Koppula P, Lei G, et al

For differentiation, cells were plated in 10% FBS-DMEM (as above) supplemented with 1 nM T 3 and 20 nM insulin (medium 1) until reaching the confluence

In addition, calcium gluconate is the preferred form for IV administration because it is less irritating to veins than calcium chloride